Semax
A synthetic analog of ACTH(4–10) studied for cognitive enhancement, neuroprotection, and BDNF expression. One of the most researched nootropic peptides.
What Is Semax?
Semax is a synthetic heptapeptide analog of the ACTH(4–10) fragment, developed at the Institute of Molecular Genetics. Unlike full-length ACTH, semax does not stimulate adrenal cortisol production—it acts selectively on neurotrophin expression and melanocortin receptor pathways in the brain. Published research documents its effects on BDNF, NGF, and cognitive function. Semax has been approved for clinical use in Russia for neurological applications.
History
Semax was developed in the 1980s at the Institute of Molecular Genetics of the Russian Academy of Sciences. The compound was designed by adding a Pro-Gly-Pro tripeptide to the C-terminus of ACTH(4–7), creating a more stable peptide with enhanced neurotropic properties and no adrenocorticotropic activity. Semax received regulatory approval in Russia in 2011 for neurological applications including cognitive impairment and stroke recovery. It has been the subject of extensive research in Russian and international scientific literature.
Certificate of Analysis (COA)
Every batch of our peptides is independently tested by third-party laboratories to verify purity, identity, and potency. We maintain 98%+ purity standards across our entire product catalog.
Shipping & Handling
All orders ship within 1-2 business days via USPS Priority or UPS Ground. Peptides are shipped in insulated packaging to maintain product integrity during transit.
Free shipping on orders over $150. Standard shipping rates apply for orders under $150. Expedited shipping options available at checkout.
All packages are shipped discreetly with no external branding or product identifiers. Tracking information is provided via email once your order ships.
All products sold on this website are intended for research and identification purposes only and are not intended for human dosing, injections, or ingestion. These products are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for legitimate laboratory research and not for human or animal consumption.
Semax
Frequently Asked Questions
What is semax?
Synthetic ACTH(4-10) analog from the Russian Academy of Sciences. Does not stimulate cortisol unlike full ACTH. Approved in Russia for neurological applications.
How much semax peptide should I take?
Sold for research purposes only. No personal usage guidance. Available in 10mg liquid vial for $125.
What is semax peptide used for?
BDNF/NGF expression, cognitive enhancement, neuroprotection in stroke/ischemia, melanocortin CNS signaling, ADHD/cognitive dysfunction research.
What does semax do?
Upregulates BDNF and NGF, enhances cognition in preclinical models, demonstrates neuroprotection. Dolotov et al. (2006) documented hippocampal BDNF/trkB effects.
Is semax safe?
Selective neurotropic activity without cortisol elevation per published research. Sold for research purposes only.
How does semax work?
Acts on neurotrophin pathways, upregulating BDNF/NGF without stimulating cortisol. Operates through melanocortin receptor signaling in the CNS.
Does the product come with instructions?
Each order includes product documentation with storage requirements and handling guidelines. For research guidance, visit our blog at /blog.
What's the actual amount in each vial?
Each vial contains the labeled amount of Semax in liquid form. The exact quantity is verified via third-party testing and documented on the batch-specific Certificate of Analysis.
Are additional supplies needed?
No. All Protocol Aminos products ship in liquid form, ready for immediate research use. No additional preparation, mixing, or supplies required.
How long does a vial last?
Shelf life depends on storage conditions. Store refrigerated at 2–8°C, away from direct light, and keep sealed when not in use. Specific stability data is available on request.