TB-500
A synthetic fragment of thymosin beta-4, one of the most studied peptides in wound healing and tissue repair research. 10mg liquid vial, 98%+ verified purity.
What Is TB-500?
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TB-500 is a synthetic peptide representing the active region of thymosin beta-4 (Tβ4), a naturally occurring 43-amino-acid protein found in virtually all human and animal cells. Thymosin beta-4 is the primary intracellular G-actin sequestering protein, playing a critical role in cell migration, differentiation, and tissue repair. Research has been published across veterinary and biomedical journals documenting effects on wound healing, cardiac tissue repair, hair follicle growth, and inflammatory response modulation.
History
Thymosin beta-4 was first isolated from the thymus gland in the 1960s by Dr. Allan Goldstein at the National Institutes of Health. The protein was initially studied for its role in immune function before researchers discovered its critical involvement in cell motility through actin binding. TB-500, representing the key active domain of thymosin beta-4, became a focus of tissue repair research in the early 2000s. Landmark studies by Bock-Marquette et al. (2004) in Nature demonstrated its cardioprotective properties, significantly expanding research interest.
Certificate of Analysis (COA)
Every batch of our peptides is independently tested by third-party laboratories to verify purity, identity, and potency. We maintain 98%+ purity standards across our entire product catalog.
Reconstitution & Storage
Reconstitute with bacteriostatic water (BAC water). Using a sterile syringe, slowly inject 1-2mL of BAC water into the vial, directing the stream against the glass wall. Do not inject directly onto the lyophilized powder. Gently swirl until fully dissolved. Do not shake.
Store unreconstituted vials at room temperature away from direct sunlight. After reconstitution, store at 2-8°C (standard refrigerator). Use within 30 days of reconstitution. Do not freeze.
For research purposes only.
Shipping & Handling
All orders ship within 1-2 business days via USPS Priority or UPS Ground. Peptides are shipped in insulated packaging to maintain product integrity during transit.
Free shipping on orders over $150. Standard shipping rates apply for orders under $150. Expedited shipping options available at checkout.
All packages are shipped discreetly with no external branding or product identifiers. Tracking information is provided via email once your order ships.
All products sold on this website are intended for research and identification purposes only and are not intended for human dosing, injections, or ingestion. These products are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for legitimate laboratory research and not for human or animal consumption.
TB-500
Frequently Asked Questions
What is TB-500?
TB-500 is a synthetic peptide representing the active region of thymosin beta-4 (Tβ4), a naturally occurring 43-amino-acid protein found in virtually all human and animal cells. It contains the key actin-binding domain responsible for the cell migration and tissue repair properties documented in published research.
What does TB-500 do?
In research settings, TB-500 is studied for its effects on cell migration, wound healing, cardiac tissue repair, and anti-inflammatory activity. Its mechanism of action centers on actin cytoskeleton reorganization and integrin-linked kinase activation, as documented in published studies including Bock-Marquette et al. (2004) in Nature.
What is TB-500 used for?
TB-500 is studied across multiple research domains: connective tissue repair, muscle regeneration, wound healing, cardiac repair following ischemic injury, and hair follicle stem cell activation. It is one of the most widely researched recovery peptides in preclinical literature.
How does TB-500 compare to BPC-157 for recovery research?
They work through different mechanisms. TB-500 acts primarily through actin binding and cell migration, while BPC-157 operates through nitric oxide and growth factor pathways. Many researchers study them together—Protocol Aminos offers a dedicated combination vial (10mg, $105) for this purpose.
Is TB-500 safe?
Published preclinical research has not reported significant adverse effects in laboratory and animal models. TB-500 has not undergone formal human clinical trials. Protocol Aminos sells TB-500 for research purposes only.
Where to buy BPC-157 and TB-500?
Protocol Aminos offers both BPC-157 ($79) and TB-500 ($89) individually, as well as a combination vial ($105). All products are third-party tested at 98%+ purity with batch-specific COAs. Free shipping on orders over $150.
How to reconstitute BPC-157 TB-500 blend?
Protocol Aminos products ship in liquid form - no preparation is required. The BPC-157 + TB-500 combination vial is ready for immediate research use directly from the vial.
Does the product come with instructions?
Each order includes product documentation with storage requirements and handling guidelines.
What's the actual amount in each vial?
Each vial contains the labeled amount of TB-500 in liquid form. The exact quantity is verified via third-party testing and documented on the batch-specific Certificate of Analysis.
Are additional supplies needed?
No. All Protocol Aminos products ship in liquid form, ready for research use. No additional preparation, mixing, or supplies required.
How long does a vial last?
Shelf life depends on storage conditions. Store refrigerated at 2–8°C, away from direct light, and keep sealed when not in use. Specific stability data is available on request.

