PT-141
A melanocortin receptor agonist studied for sexual function, CNS signaling, and neuroendocrine pathways.
What Is PT-141?
PT-141 (bremelanotide) is a synthetic cyclic heptapeptide that acts as an agonist of the melanocortin-4 receptor (MC4R). Originally derived from melanotan II, PT-141’s mechanism operates through the central nervous system rather than the vascular system. It received regulatory approval in 2019 under the brand name Vyleesi for a specific clinical application.
History
PT-141 emerged from research into melanocortin peptides conducted at the University of Arizona in the 1990s. Researchers studying melanotan II (a synthetic tanning peptide) observed unexpected effects on sexual arousal during clinical trials, leading to the development of PT-141 as a more targeted compound. Bremelanotide was developed by Palatin Technologies and ultimately received regulatory approval in 2019 after extensive clinical trials demonstrated its CNS-mediated mechanism of action.
Certificate of Analysis (COA)
Every batch of our peptides is independently tested by third-party laboratories to verify purity, identity, and potency. We maintain 98%+ purity standards across our entire product catalog.
Shipping & Handling
All orders ship within 1-2 business days via USPS Priority or UPS Ground. Peptides are shipped in insulated packaging to maintain product integrity during transit.
Free shipping on orders over $150. Standard shipping rates apply for orders under $150. Expedited shipping options available at checkout.
All packages are shipped discreetly with no external branding or product identifiers. Tracking information is provided via email once your order ships.
All products sold on this website are intended for research and identification purposes only and are not intended for human dosing, injections, or ingestion. These products are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for legitimate laboratory research and not for human or animal consumption.
PT-141
Frequently Asked Questions
What is PT-141?
PT-141 (bremelanotide) is a synthetic melanocortin-4 receptor agonist. Originally derived from melanotan II, operates through the CNS. Received regulatory approval in 2019 as Vyleesi.
How long does PT-141 last?
Published clinical research documents duration of activity. Protocol Aminos sells PT-141 for research only. Consult pharmacokinetic literature for study design.
Where to buy PT-141?
Protocol Aminos: 10mg liquid vial for $69. Third-party tested at 98%+ purity with batch-specific COA. Free shipping over $150.
What does PT-141 do for women?
PT-141 acts through melanocortin CNS receptors. Its FDA application (Vyleesi) is indicated for premenopausal women. Sold for research purposes only.
Does PT-141 increase testosterone?
PT-141 acts through melanocortin CNS pathways, not direct hormonal pathways. Mechanism is distinct from testosterone-modulating compounds.
What does PT-141 do?
Studied for MC4R agonism, CNS signaling, neuroendocrine regulation, and melanocortin system roles. Operates through central rather than vascular mechanisms.
How does PT-141 work?
Activates MC3R/MC4R in the CNS. Effects mediated through CNS signaling as documented by Diamond et al. and others.
Does the product come with instructions?
Each order includes product documentation with storage requirements and handling guidelines. For research guidance, visit our blog at /blog.
What's the actual amount in each vial?
Each vial contains the labeled amount of PT-141 in liquid form. The exact quantity is verified via third-party testing and documented on the batch-specific Certificate of Analysis.
Are additional supplies needed?
No. All Protocol Aminos products ship in liquid form, ready for immediate research use. No additional preparation, mixing, or supplies required.
How long does a vial last?
Shelf life depends on storage conditions. Store refrigerated at 2–8°C, away from direct light, and keep sealed when not in use. Specific stability data is available on request.