{"product_id":"mots-c","title":"MOTS-C","description":"\u003cp dir=\"ltr\"\u003e\u003cspan\u003eA 16-amino-acid peptide encoded by mitochondrial DNA, studied for metabolic regulation, exercise mimetic properties, and longevity research.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eWhat Is MOTS-C?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eMOTS-C (mitochondrial open reading frame of the 12S rRNA-c) is a mitochondria-derived peptide encoded by the mitochondrial genome. Discovered by Dr. Changhan David Lee’s research group at USC, MOTS-C represents a relatively new class of signaling molecules. Published research has shown MOTS-C activates AMPK, a master metabolic regulator, and has been described as an “exercise mimetic.”\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eHistory\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eMOTS-C was discovered in 2015 by Dr. Changhan David Lee and colleagues at the University of Southern California Leonard Davis School of Gerontology. The peptide was identified through computational analysis of the mitochondrial genome, revealing previously unrecognized open reading frames encoding bioactive peptides. The discovery of MOTS-C and its sister peptide humanin opened an entirely new field of research into mitochondria-derived peptides (MDPs) as intercellular signaling molecules. Subsequent research demonstrated MOTS-C’s role in metabolic regulation, exercise physiology, and aging.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Protocol Aminos","offers":[{"title":"10MG","offer_id":44808017575981,"sku":null,"price":69.0,"currency_code":"COP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0744\/2232\/1197\/files\/MOTS-C.png?v=1775605969","url":"https:\/\/protocolaminos.com\/products\/mots-c","provider":"Protocol Aminos","version":"1.0","type":"link"}